発表論文

イナリサーチが発表した論文をお知らせします。

発表論文(2009-)

発表年
発表論文
2019Anzai T (安齋享征) , Matsuyama T, Wasko M, Hatakeyama H (畠山洋文), Horikawa S(堀川真一), Anzai R, Iwata H (岩田聖), Imai N, Mizuhashi F, Tsuboi M, Okuzono T, Takagi H, Cho H, Bryan Tan Siang Rong, Masaki F, and Nakae D. Establishment of the Global SEND Alliance (G-SEND) in Japan and efficient creation of electronic SEND datasets between CROs. J. Toxicol Pathol. Vol.32, 119–126 (2019)
2019Yamagiwa Y, Takei Y (武井由弘), Koizumi H (小泉治子), Nemoto S, Kurata M, Satoh H. Pathological Features of Corneal Phospholipidosis in Juvenile White Rabbits Induced by Ocular Instillation of Chloroquine or Amiodarone. Toxicol Pathol. Vol.47, 26–34 (2019)
2018Koeda A(小枝暁子), Iwao T, Nakanishi A, Mizuno S, Yamashita M, et al. Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes. Drug Metabolism and Pharmacokinetics. 2019 (in press)
2018Onozato D, Yamashita M, Fukuyama R, Akagawa T, Koeda A(小枝暁子), et al. Efficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic Functions. Stem Cells and Development vol.27(15)
2018 Sutou S, Koeda A (小枝暁子), Komatsu K (小松佳奈), Shiragiku T, Seki H, Yamakage K, Niitsuma T, Kudo T, Wakata A. Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests. Genes Environment. 2018; 40: 20.
2018Mochizuki H(望月秀美), Murota N(室田尚哉), Sato S(佐藤伸一), et al. Approaches of validation of a 2-week combined repeated oral dose toxicity study with plasma micro sampling toxicokinetics (PMS-TK) in common marmosets. The Journal of Toxicological Sciences. 2018; 43(11), 685-695
2018Atsushi Fujiwara(藤原淳), Miki Shimosawa(下澤美紀), Masahiko Iino(飯野雅彦), Mikio Sasaki(佐々木幹夫), Shin-ichi Sato(佐藤伸一), Akihito Shimoi(下井昭仁).Generalization tests using different dosing routes from those of drug discrimination training in rats. J Toxicol Sci. 2018;43(7):451-458.
2018Yasushi Torii, Mikio Sasaki(佐々木幹夫), Min-Chul Shin, Norio Akaike, Ryuji Kaji. Comparison of efficacy and toxicity between botulinum toxin subtypes A1 and A2 in cynomolgus macaques. Toxicon. 2018; 153, 114-119
2018Atsushi Watanabe, Kazuyuki Tsurui, Shigeki Yoneyama(米山茂樹), Hijiri Iwata(岩田聖), Takayuki Anzai(安齋享征), et al. Effect of dosing frequency of teriparatide (PTH 1-34) on bone formation in rats: comparison of bone metabolism marker levels. The Journal of Toxicological Sciences. 2018; 43(7), 435-442
2018Yamazaki D, Kitaguchi T, Oguchi M(小口正夫), et al.Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes. Journal of Pharmacological Sciences.2018; 136(4), 249-256
2018Matsuo T, Uchida T, Takei S(武井信貴子), Ido D(井戸大介), Tanaka M(田中守), Oguchi M(小口正夫), et al. Visual evoked potential in rabbits’ eyes with subretinal implantation by vitrectomy of Okayama University-type retinal prosthesis (OURePTM). Journal of Veterinary Medical Science. 2018; 80(2), 247-259
2017Matsuo T, Uchida T, Takei S(武井信貴子), Ido D(井戸大介), Tanaka M(田中守), Oguchi M(小口正夫), et al.Subretinal implantation of Okayama University-type retinal prosthesis (OURePTM) in canine eyes by vitrectomy. Journal of Veterinary Medical Science. 2017; 79(12), 1939-1946
2017Nakata H,Tsubotani Y,Nii T,Hagi A,Inoue Y and Imamura T(今村匡志).Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. Journal of Medical Microbiology. 2017.
2017Kitaguchi T,Otabe K(小田部耕二),Oguchi M(小口正夫),et al.CSAHi study: Detection of drug-induced ion cannnel/receptor responses, QT prolongation, and arrhythmia using multi-electrode arrays in combination with human induced pluripotent stem cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods. 2017.
2017Ando H, Tashibu H(田澁弘行), Sekino Y, et al. A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes. Journal of Pharmacological and Toxicological Methods. 2017; 84, 111-127.
2016Yamamoto W, Tashibu H(田澁弘行), Sekino Y, et al. Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential. journal. pone. 2016; 11(12).
2016Shiba Y,Sakamoto K(坂本憲吾),Ido D(井戸大介),et al.Allogeneic Transplantation of iPS Cell-Derived Cardiomyocytes Regenerates Primate Hearts.Nature.2016;Volume 538,October 20.
2016Fujiwara A(藤原淳), Iino M(飯野雅彦), Sasaki M(佐々木幹夫). Relationship between the Dose to Produce Reinforcing Effect and that of Gross Behavioral Effects in Rhesus Monkeys. J Drug Abuse. 2016; 2:2.
2016武井信貴子.AAALAC International(旧国際実験動物ケア評価認証協会)による認証.実験動物と環境.2016; 24(2): 101-104.
2016Kitaguchi T,Otabe K(小田部耕二),Oguchi M(小口正夫),et al.CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythimia – Effects of 7 reference compounds at 10 facilities. Journal of Pharmacological and Toxicological Methods. 2016; 78: 93-102.
2016Fujiwara A(藤原淳), Shimosawa M(下澤美紀), Iino M(飯野雅彦), Sasaki M(佐々木幹夫), Sato S(佐藤伸一). Physical Dependence and Plasma Concentrations of Morphine in Rats. J Drug Abuse. 2016, 2:3.
2015Shiina T, Yamada Y(山田幸穂), Ido D(井戸大介), Yamanaka H(山中久), et al. Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing: Mafa-class I polymorphism. Immunogenetics. 2015; 67(10), 563-78
2015Onodera H, Sasaki S, Otake S, Tomohiro M, Shibuya K, Nomura M(野村護). General considerations in ocular toxicity risk assessment from the toxicologists’ viewpoints. The Journal of Toxicological Sciences.2015; 40(3):295-307.
2015ELMORE S, CORA M, GRUEBBEL M, HAYES S, HOANE J, KOIZUMI H(小泉治子), PETERS R, ROSOL T, SINGH B, SZABO K. Proceedings of the 2014 National Toxicology Program Satellite Symposium. Toxicologic Pathology.  2015; 43: 10-40.
2015Hamada S, Imamura T(今村匡志),et al. CSGMT(共同研究). Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: Summary of the collaborative Study Group for CSGMT/JEMS・MMS. Mutation Research. 2015;780-781:2-17.
2015Imamura T(今村匡志), Koeda A(小枝暁子), Morimoto K(森本清), Hatakeyama H(畠山洋文), Suzuki H(鈴木洋), Wakao Y, Kawasako K, Otabe K(小田部耕二), Sato S(佐藤伸一). Evaluation of a repeated-dose liver micronucleus assay with 2,6-dinitrotoluene using young adult rats. Mutation Research. 2015;780-781:46-50.
2015Inoue S(井上紗季), Yonemaru K, Yanai T, Sakai H. Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret. J. Vet. Med. Sci. 2015; 77(2): 225-228.
2014Tazawa S, Katayama S, Hirabayashi M, Yamaguchi D, Nakamura S. Improvement of Surface Functionalities, Including Allergenicity Attenuation, of Whole Buckwheat Protein Fraction by Maillard-Type Glycation with Dextran. Prev. Nutr. Food Sci. 2014; 19(4): 327-332.
2013Nakano M, Suzuki H, Imamura T, Lau A, Lynch B. Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQTM). Regulatory Toxicology and Pharmacology. 2013; 67: 189-197.
2013Ema M, Imamura T, Suzuki H, Kobayashi N, Naya M, Nakanishi J. Genotoxicity evaluation for single-walled carbon nanotubes in a battery of in vitro and in vivo assays. J. Appl. Toxicol. 2013; 33: 933-939.
2012新薬開発における心毒性評価;前臨床試験での経験.第14回臨床薬理試験研究会.セッションII 新薬開発における心毒性評価.2012年6月9日開催.臨床医薬.2012;28(10);895-902.
2012Ema M, Imamura T, Suzuki H, Kobayashi N, Naya M, Nakanishi J. Evaluation of genotoxicity of multi-walled carbon nanotubes in a battery of in vitro and in vivo assays. Regulatory Toxicology and Pharmacology. 2012; 63: 188-195.
2011Ema M, Matsuda A, Kobayashi N, Naya M, Nakanishi J. Evaluation of dermal and eye irritation and skin sensitization due to carbon nanotubes. Regulatory Toxicology and Pharmacology. 2011;61:276-281.
2011Umigai N, Murakami K, M.V.Ulit, L.S.Antonio, Shirotori M, Morikawa H, Nakano T. The Pharmacokinetic profile of crocetin in healthy adult human volunteers after a single oral administration. Phytomedicine. 2011;18:575-578.
2011Suzuki H,Imamura T, Koeda A, Morimoto K, Wakasa Y, Takei Y, Amemiya R, Hatakeyama H, Satoh H, Sato S. Genotoxicity studies of 2,6-dinitrotoluene (2,6-DNT). The Journal of Toxicological Sciences. 2011;36(4):499-505.
2010モキシフロキサシンの健康成人フィリピン人被験者におけるQT/QTc評価試験. 臨床医薬. 2010;26(12): 841-851.
2010心電図異常評価に関するICH-S7B(非臨床試験) 及びE14(臨床試験)-厚生労働省通知の意義-. 臨床評価.2010;38(1): 51-56.
2010Thorough QT/QTc試験 (QT/QTc評価試験): ICH E14に基づく試験の実際と日本製薬企業への提案. 臨床評価.2010;38(1): 41-49.
2009Tanaka N, Sasaki K, Hayashi K, Sakai A, Asada S, Muramatsu D, Kuroda S, Mizuhashi F, Nagai M, Suzuki H,Imamura T, Asakura M, Satoh H, Sakamoto A, Nakao R, Hirose H, Ishii N, Umeda M. An Interlaboratory Collaborative Study on a Cell Transformation Assay Using Bhas 42 Cells. AATEX. 2009; 14(1): 831-848.
2009Thorough QT/QTc試験(綿密なQT/QTc試験)-ICHガイドラインE14に基づく試験の実際-. 医薬ジャーナル. 2009;45(4):115-119.